5:00 p.m. – 7:00 p.m.

In Memoriam of Professor Witold Drabikowski session: Calcium and motility

5:00 p.m. – 5:10 p.m.

Chair:
Jacek Kuznicki (International Institute of Molecular and Cell Biology, Warsaw)
Special guests: Hanna Strzelecka-Golaszewska, Anna Jakubiec-Puka, Stefan Angielski

5:10 p.m. – 5:20 p.m.

Movie about Witold Drabikowski

5:20 p.m. – 5:45 p.m.

Ernesto Carafoli (University of Padova, Italy)
Witold Drabikowski: a great scientist and a friend

5:45 p.m. – 6:10 p.m.

Zenon Grabarek (Boston Biomedical Research Institute, Watertown, USA)
EF-hand structure and the role of magnesium in calcium signaling

6:10 p.m. – 6:35 p.m.

Marek Michalak (University of Alberta, Edmonton, Canada)
Calcium buffering chaperones

6:35 p.m. – 7:00 p.m.

David H. MacLennan (University of Toronto, Canada)
Mechanistic Models for Muscle Diseases Related to the Ryanodine Receptor

7:00 p.m. – 9:00 p.m.

Get-together party – wine and snacks

9:00 a.m. – 11:00 am.

I session - Calcium imaging

Chair:
Grzegorz Grynkiewicz (Pharmaceutical Research Institute, Warsaw) and Claus Heizmann (Professor emeritus, University of Zürich, Switzerland)

9:00 a.m. – 9:30 a.m.

Olga Garaschuk (Eberhard Karls Universität Tübingen, Germany)
In vivo Ca signaling in microglia

9:30 a.m. – 10:00 a.m.

Spencer LaVere Smith (The Wolfson Institute for Biomedical Research, University College London, UK)
Imaging calcium dynamics in neurons during sensory processing in vivo

10:00 a.m. – 10:20 a.m.

Dorota Wypych, Paweł Pomorski
(Nencki Instiute of Experimental Biology, Warsaw, Poland)
Subcellular visualization of calcium signal formation in glioma C6 cells

10:20 a.m. – 10:40 a.m.

Kenta Saito, Noriyuki Hatsugai, Kazuki Horikawa, Kentaro Kobayashi, Toru Matsu-ura, Katsuhiko Mikoshiba and Takeharu Nagai
(Hokkaido University, Japan; RIKEN, Japan; JST, Japan)
Auto-luminescent genetically-encoded ratiometric indicator for real-time Ca²⁺ imaging at the single cell level

10:40 a.m. – 11:00 a.m.

Valentina Lissandron, Tullio Pozzan and Paola Pizzo
(University of Padua and CNR Institute of Neuroscience, Padua, Italy)
Unique characteristics of Ca²⁺ homeostasis of the trans-Golgi compartment

11:00 a.m. – 1:00 p.m.

Tuesday Poster Session

1:00 p.m. – 2:00 p.m.

Lunch

2:00 p.m. – 4:00 p.m.

II session – Calcium and neuronal function
supported by the Committee on Neurobiology, Polish Academy of Sciences

Chair:
Jan Albrecht (Medical Research Center, Warsaw) and Jan Lehotsky (Comenius University, Martin, Slovakia)

2:00 p.m. – 2:30 p.m.

Vladimir Parpura (University of Alabama at Birmingham, AL USA)
Ca²⁺ sources for the exocytotic glutamate release from astrocytes

2:30 p.m. – 3:00 p.m.

Alexei Verkhratsky (University of Manchester, UK)
Calcium signals provide the substrate for glial excitability

3:00 p.m. – 3:20 p.m.

Amalia M. Dolga, Julia Grohm, Stefanie Pfeifer, Svenja Tobaben, Carsten Culmsee
(Instiute fuer Pharmacologie und Klinische Pharmazie, Phillips Universitaet Marburg, Germany)
Activation of small conductance K_Ca2 channels prevents neuronal death induced by delayed calcium deregulation

3:20 p.m. – 3:40 p.m.

Joanna Jung, Helen Coe, Allison Kraus and Marek Michalak
(School of Molecular and System Medicine, University of Alberta, Canada)
The role of endoplasmic reticulum quality control system in the biology of the major peripheral myelin glycoproteins

3:40 p.m. – 4:00 p.m.

Niklas Schütter and Olaf Pongs
(Institute for Neural Signal Transduction, ZMNH, Hamburg, Germany)
In vivo labeling of T-Type Ca²⁺ Channel with Ephluorin

4:00 p.m. – 4:30 p.m.

Coffee break

4:30 p.m. – 6:40 p.m.

III session - Calcium toolkit
supported by the EC FP7 grant "Proteins in Health and Disease", HEALTH-PROT, GA No 229676

Chair:
Anna Filipek (Nencki Institute of Experimental Biology, Warsaw) and Walter Chazin (Vanderbilt University, Nashville, USA)

4:30 p.m. – 5:00 p.m.

Mitsu Ikura (University of Toronto, Canada)
Structural basis of calcium signal encoding mechanisms

5:00 p.m. – 5:30 p.m.

Olga Moroz (University of York, Heslington, UK)
Role of zinc-calcium interplay in the structure and function of human S100A12

5:30 p.m. – 6:00 p.m.

David B. Sacks (Harvard Medical School, Boston Massachusetts, USA)
Calmodulin and calmodulin-binding proteins in cancer

6:00 p.m. – 6:20 p.m.

Michael Koch, Christine Betz, Seth Chatiyat, Walter J. Chazin, and Guenter Fritz
(University of Konstanz, Germany; University of Freiburg, Germany; Vanderbilt University, USA)
Structural basis of S100-RAGE interaction

6:20 p.m. – 6:40 p.m.

Hannah V. McCue, Robert D. Burgoyne, Lee P. Haynes
(University of Liverpool, England)
Membrane targetting of the EF-hand containing calcium sensing proteins Calneurons I and II (CaBP8 and CaBP7)

6:45 p.m.

Presentation of diplomas to the Recipients of Travel Scholarships funded by European Calcium Society, School of Molecular Medicine and Warsaw Organizers.

7:00 p.m.

ECS General Assembly

9:00 a.m. – 11:00 a.m.

IV session – Calcium signaling

Chair:
Jolanta Baranska (Nencki Institute of Experimental Biology, Warsaw) and Stephen Moss (University College London, UK)

9:00 a.m. – 9:30 a.m.

James W. Putney (National Institute of Environmental Health Sciences NIH, Research Triangle Park, NC USA)
Regulation and Physiological Function of Store-operated Calcium Entry

9:30 a.m. – 10:00 a.m.

Martin D. Bootman (The Babraham Institute, Cambridge, UK)
Calcium signalling during excitation-contraction coupling in atrial myocytes

10:00 a.m. – 10:20 a.m.

Giovanni Monaco, Elke Decrock, Tim Ulens, Haidar Akl, Ludwig Missiaen, Marc De Maeyer, Luc Leybaert, Clark W. Distelhorst, Jan B. Parys, Humbert De Smedt and Geert Bultynck
(K.U. Leuven, Belgium; Western Reserve University, USA)
The BH4 domains of Bcl-2 and Bcl-Xl differentially regulate inositol 1,4,5-trisphosphate receptors and apoptosis

10:20 a.m. – 10:40 a.m.

Alexander M. Lewis, Carmen H. Coxon, Amanda J. Sadler, Sridhar R. Vasudevan, R. Duncan Campbell, Jon M. Gibbins, Katherine L. Tucker
(University of Oxford, UK; University of Reading, UK)
NAADP Regulates Human Platelet Function

10:40 a.m. – 11:00 a.m.

Hideki Shibata, Hirofumi Sugiura, Takeru Yokoyama, Stepen E. Moss, Masatoshi Maki
(Nagoya University, Japan; University College London, UK)
Recruitment of annexin A11 to endoplasmic reticulum exit sites is mediated by the adaptor function of the penta-EF-hand protein ALG-2

11:00 a.m. – 1:00 p.m.

Wednesday Poster Session

1:00 p.m. – 2:00 p.m.

Lunch

2:00 p.m. – 2:15 p.m.

Presentation of equipment by PerkinElmer Company

2:15 p.m. – 4:25 p.m.

V session – Calcium and gene expression in differentiation
supported by the Committee on Cell Biology, Polish Academy of Sciences

Chair:
Wieslawa Lesniak (Nencki Institute of Experimental Biology, Warsaw) and Joachim Krebs (Max Planck Institute for Biophysical Chemistry, Göttingen, Germany)

2:15 p.m. – 2:45 p.m.

Catherine Leclerc (Universite Paul Sabatier, Toulouse, France)
Calcium signaling and gene expression during early neurogenesis in Xenopus laevis

2:45 p.m. – 3:15 p.m.

Jose Naranjo (Centro Nacional de Biotecnología, Madrid, Spain)
DREAM regulates synaptic plasticity in the hippocampus

3:15 p.m. – 3:45 p.m.

Douglas L. Black (Howard Hughes Medical Institute, Los Angeles, USA)
Mechanisms and Programs of Neuronal Alternative Pre-mRNA Splicing

3:45 p.m. – 4:05 p.m.

Ewa Kilanczyk, Slawomir Filipek, Anna Filipek
(Nencki Institute of Experimental Biology, Poland; International Institute of Molecular and Cell Biology, Poland)
The influence of CacyBP/SIP and S100A6 on the level of P-ERK1/2 kinases and on cell differentiation

4:05 p.m. – 4:25 p.m.

Tommie V. McCarthy, Alison Corr, Limian Zheng, Thomas Grunström, David H. Lovett, John J. Mackrill
(University College Cork, Ireland; Umea University, Sweden; San Francisco Veterans Affairs Medical Center, USA)
Ca²⁺-dependent repression of the matrix metalloprotease-2 gene

4:25 p.m. – 5:00 p.m.

Coffee break

5:00 p.m. – 7:00 p.m.

VI session – Calcium transport

Chair:
Ludmila Zylinska (Medical University of Lodz, Poland) and Jan Parys (Katholieke Universiteit Leuven, Belgium)

5:00 p.m. – 5:30 p.m.

Ludwig Neyses (Manchester Royal Infirmary, UK)
Novel and unexpected role of the sarcolemmal calcium pumps (PMCAs) in the heart

5:30 p.m. – 6:00 p.m.

Antony Galione (University of Oxford, UK)
Physiological roles of NAADP receptors

6:00 p.m. – 6:20 p.m.

Géza Antalffy, Katalin Pászty, Yuning Xiong, Rita Padányi, Krisztina Lór, Emanuel E. Strehler and Ágnes Enyedi
(National Blood Center, Hungary; Semmelweis University, Hungary; Mayo Clinic College of Medicine, USA)
Regulation of the apical localization of PMCA2w/b in polarized epithelia

6:20 p.m. – 6:40 p.m.

Jill Thompson, Trevor Shuttleworth, Olivier Mignen
(University Of Rochester Medical Center, USA; Université de Bretagne Occidentale, France)
ORAI3 and the selective activation of the ARC channel by arachidonic acid

6:40 p.m. – 7:00 p.m.

Thomas Henzi, Oliver Arendt, Carl J. Christel, Raphael Schaer, Lisa Kreiner, Detlev Grabs, Hartmut Schmidt, Jens Eilers, Amy Lee, Beat Schwaller
(University of Fribourg, Switzerland; Carl-Ludwig Institute of Physiology, Germany; University of Iowa, USA)
Calretinin interacts with an intracellular loop of Cav2.1 Ca²⁺ channels and regulates Cav2.1 function

7:30 p.m.

Dinner for all participants – Villa Foksal Restaurant, 3/5 Foksal Street – transfer by bus provided by the Organizers

9:00 a.m. – 11:00 a.m.

VII session – Calcium and diseases

Chair:
Urszula Wojda (International Institute of Molecular and Cell Biology, Warsaw) and Roland Pochet (Universite Libre de Bruxelles, Belgium)

9:00 a.m. – 9:30 a.m.

Simonetta Camandola (National Institute on Aging, Baltimore, USA)
Calcium in Neuronal Plasticity and Alzheimer’s Disease

9:30 a.m. – 10:00 a.m.

Carlos Enrich (University of Barcelona, Spain)
Annexin A6 induces cholesterol imbalance and Ras inactivation

10:00 a.m. – 10:20 a.m.

Virginie Robert, Pierre-Emmanuel Paulet, Marc Moreau, Catherine Leclerc, Jean-Charles Guéry, Lucette Pelletier
(INSERM U563, Toulouse, France)
Th2 lymphocytes selectively expressed Ca_V1 channels that may represent a therapeutic target in allergic diseases

10:20 a.m. – 10:40 a.m.

Timothy Logue, Estelle Leclerc, Stefan Vetter
(Florida Atlantic University, USA; North Dakota State University, USA)
Binding of S100B to the V-domain of RAGE: A Comparative Study

10:40 a.m. – 11:00 a.m.

Cristina Pierro, Martin D. Bootman, Simon J. Cook, H. Llewelyn Roderick
(Babraham Institute, UK; University of Cambridge, UK)
The role of calcium signalling in oncogenic transformation

11:00 a.m. – 11:30 a.m.

Coffee break

Voting for the best poster and best oral presentation (Drabikowski award)

11:30 a.m. – 12:30 p.m.

Sir Michael Berridge lecture

Chair: Volker Gerke (University of Münster, Germany) and Agnes Enyedi (National Blood Center, Budapest, Hungary)

Katsuhiko Mikoshiba (RIKEN BSI and JST, Japan)
IP₃ receptor: the structure-function and its role in cell function and disease

12:35 p.m.

Awards ceremony

Announcement of the Conference ECS 2012

1:00 p.m.

The end of the meeting